中科院海洋研究所研究员,博士生导师。长期在无脊椎动物特别是虾类繁殖生物学、功能基因组学和遗传育种方面开展科学探索、技术研发,取得一系列创新性成果。主持国家级科研项目20余项,包括国家重点研发计划项目1项,国家自然科学基金重点项目1项、国家基金委国际(地区)合作项目2项、国家自然科学基金面上项目6项、国家863计划项目4项以及国家产业体系岗位科学家项目等。以第一或通讯作者在Nature Communication、PLoS Biology等发表SCI收录论文80余篇;获国家发明专利授权20余项,国际PCT专利授权2项;培育虾类国审新品种3个;获得省部级奖励5项。 |
l 1993.09–1999.07,中国科学院海洋研究所,博士学位; l 1987.09–1990.10,厦门大学,硕士学位; l 1983.09–1987.07,厦门大学,学士学位; |
l 2001.10 -至今,中国科学院海洋研究所,研究员; l 2009.02-2009.3,澳大利亚CSIRO动物研究所,高级访问学者; l 2005.01-2005.04,法国蒙彼利埃第二大学,高级访问学者; l 1996.02-2001.10,中国科学院海洋研究所,副研究员; l 1998.01-1999.05,美国康涅狄格大学,访问学者; l 1993.02-1996.02,中国科学院海洋研究所,助理研究员。 |
1、 国家重点研发计划项目,重要养殖虾蟹类种质创制和健康苗种繁育(2018YFD0901300),2018.12-2022.12,2791万元,主持,在研 2、 国家自然科学基金重点基金项目,凡纳滨对虾抗副溶血弧菌性状的遗传基础及调控机制研究(31830100),2019.1-2023.12,291万元,主持,在研 3、 国家自然科学基金委国际合作项目,十足目甲壳动物生殖过程的多重调控机制:性别决定和性别分化的分子桥梁(31861143047),2019.1-2021.12,160万元,主持,在研 4、 国家虾蟹产业技术体系岗位科学家项目,药物靶位开发(CARS-48),2016.1-2020,12,350万元,主持,在研; 5、 中国科学院A类先导专项项目子课题,虾、贝增产培优品种的精准设计(XDA24030105), 600万元,主持,在研; 6、 国家自然科学基金面上项目,凡纳滨对虾重组激活基因RAGs的结构与功能研究(41776158),70万元,主持,在研; |
1. Fei Liu*, Shihao Li*, Yang Yu, Mingzhe Sun, Jianhai Xiang, Fuhua Li *, 2020. Effects of ammonia stress on the hemocytes of the Pacific white shrimp Litopenaeus vannamei. Chemosphere 239 (2020) 124759. 2. Xiaojun Zhang #, Jianbo Yuan#, Yamin Sun#, Shihao Li#, Yi Gao#, Yang Yu#, Chengzhang Liu, Quanchao Wang, Xinjia Lv, Xiaoxi Zhang, Ka Yan Ma, Xiaobo Wang, Wenchao Lin, Long Wang, Xueli Zhu, Chengsong Zhang, Jiquan Zhang, Songjun Jin, Kuijie Yu, Jie Kong, Peng Xu, Jack Chen, Hongbin Zhang, Patrick Sorgeloos, Amir Sagi, Acacia Alcivar-Warren, Zhanjiang Liu, Lei Wang, Jue Ruan, Ka Hou Chu*, Bin Liu*, Fuhua Li* & Jianhai Xiang*, 2019. Penaeid shrimp genome provides insights into benthic adaptation and frequent molting. Nature Communications (2019) 10:356. 3. Shihao Li, Xinjia Lv, Fuhua Li*, Jianhai Xiang, 2019. Characterization of a lymphoid organ specific anti-lipopolysaccharide factor from shrimp reveals structure-activity relationship of the LPS-binding domains. Frontiers in Immunology. Frontiers in Immunology 10: 872. 4. Zhang Q+, Yu Y+, Wang Q, Liu F, Luo Z, Zhang C, Zhang X, Huang H, Xiang J and Li F* (2019) Identification of Single Nucleotide Polymorphisms Related to the Resistance Against Acute Hepatopancreatic Necrosis Disease in the Pacific White Shrimp Litopenaeus vannamei by Target Sequencing Approach. Front. Genet. 10:700. 5. Yang Yu+, Quanchao Wang+,Qian Zhang,Zheng Luo,Yue Wang,Xiaojun Zhang,Hao Huang,Jianhai Xiang,Fuhua Li*,2019. Genome Scan for Genomic Regions and Genes Associated with Growth Trait in Pacific White Shrimp Litopeneaus vannamei. Marine Biotechnology 21:374-383. 6. Chengsong Zhang, Fang Su, Shihao Li, Yang Yu, Jianhai Xiang, Jianguo Liu*, Fuhua Li*, 2018. Isolation and identification of the main carotenoid pigment from a new variety of the ridgetail white prawn Exopalaemon carinicauda. Food Chemistry 269 (2018) 450–454. 7. Shihao Li?, Zhiwei Wang?, Fuhua Li *, Kuijie Yu and Jianhai Xiang,2017. A Novel Vascular Endothelial Growth Factor Receptor Participates in White Spot Syndrome Virus Infection in Litopenaeus vannamei. Front. Immunol. 8:1457. 8. Hui Yang, Shihao Li, Fuhua Li* and Jianhai Xiang, 2016. Structure and Bioactivity of a Modified Peptide Derived from the LPS-Binding Domain of an Anti-Lipopolysaccharide Factor (ALF) of Shrimp. Marine Drugs 2016, 14, 96. 9. Fuhua Li, Jianhai Xiang, 2013. Recent advances in researches on the innate immunity of shrimp in China. Developmental and Comparative Immunology 39: 11-26. 10. Fuhua Li, Jianhai Xiang, 2013. Signaling pathways regulating innate immune responses in shrimp. Fish and Shellfish Immunology 34:973-980. |
1、 Li S., Li F*. (2020) The Anti-lipopolysaccharide Factors in Crustaceans. In: Hoeger U., Harris J. (eds) Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and other Body Fluid Proteins. Subcellular Biochemistry, vol 94. Springer, Cham. |
1、 李富花 李诗豪 郭书悦 相建海,一种线性的合成多肽G及其抗病毒应用. ZL 2013 1 0534388.9 2、 李富花、李诗豪、郭书悦、相建海,一种环状的合成多肽A 及其抗菌抗病毒应用. ZL2013 1 0534929.8 3、 李富花、李诗豪、郭书悦、相建海。一种环状的合成多肽B 及其抗菌抗病毒应用. ZL2013 1 0534912.2 4、 李富花,李诗豪,郭书悦,相建海。一种环状的合成多肽
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